Amidine Sulfonamides and Benzene Sulfonamides: Synthesis and Their Biological Evaluation
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چکیده
منابع مشابه
Amide derivatives of sulfonamides and isoniazid: synthesis and biological evaluation.
In the present study, various amide derivatives of sulfanilamide, sulfamethoxazole, sulfadiazine, dapsone and isoniazid have been synthesized by condensing them with appropriate 4-oxo-4-(4-substituted phenyl)butanoic acid moiety. The compounds have been evaluated for their antiinflammatory, ulcerogenic and antibacterial activities. Their structures were established on the basis of elemental ana...
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In the present study, a series of N-substituted derivatives of 2-phenylethylamine has been synthesized. The reaction of 2-phenylethylamine (1) with benzene sulfonyl chloride (2) yielded N-(2-phenylethyl) benzenesulfonamide (3), which further on treatment with alkyl/acyl halides (4a-i) in the presence of sodium hydride furnished into N-substituted sulfonamides (5a-i). These derivatives were cha...
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ژورنال
عنوان ژورنال: Journal of Chemistry
سال: 2015
ISSN: 2090-9063,2090-9071
DOI: 10.1155/2015/524056